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However there are a lot of external magnetic field
2023-09-01

However, there are a lot of external magnetic field disturbances in urban environments, for example when the AHRS is close to a ferrous or magnetic object, which will disturb the output of magnetometer, then the observational errors cannot satisfy the assumption of Kalman filtering, and so, the atti
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Herein we employ an adapted
2023-09-01

Herein we employ an adapted targeted quantitative proteomic isotope dilution method, developed in our laboratory [[18], [19], [20], [21]], to quantify membrane transporters in fresh lung from five donors, in four immortalized human lung cell lines and in three control cell lines. We quantify twelve
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In fact serotonin is a major modulator of dopaminergic DA
2023-09-01

In fact, serotonin is a major modulator of dopaminergic (DA) neuronal activity through the 5-HT2C receptor. Studies have shown that the selective 5-HT2C receptor agonist Ro60-0175 blocks the burst-firing of mesolimbic DA neurons, which project from the ventral tegmental area (VTA) to the nucleus acc
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Regenerative mechanisms often require reemployment of pathwa
2023-09-01

Regenerative mechanisms often require reemployment of pathways used during development in the embryonic and postnatal periods (Waschek, 2002). PACAP has diverse neurodevelopmental and growth factor-like effects (Botia et al., 2007; Vaudry et al., 2009; Waschek, 2002; Watanabe et al., 2016) and it is
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Since the localization of LO depends
2023-08-31

Since the localization of 5-LO depends on phosphorylation, we also analyzed the phosphorylation profile of 5-LO-WT and all isoforms by Western blot using specific Dextran sulfate sodium salt against the phosphorylation sites S271 and S523. Whereas phosphorylation at S271 activates the 5-LO, inhibits
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In an AP scenario several
2023-08-31

In an AP scenario, several inflammatory mediators are produced locally to orchestrate an immune response. Eicosanoids are among those molecules and represent a class of lipid mediators synthesized from arachidonic SIS3 through the action of cyclooxygenases or lipoxygenases to generate prostaglandin
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For both the hydroxylation and lyase reactions the
2023-08-31

For both, the 17α-hydroxylation and 17, 20-lyase reactions, the heme iron center of P450 17A1 receives electron reducing equivalents from CPR. Both reactions require one pair of electrons and molecular oxygen for the conversion of the substrate into product in each catalytic cycle. However, the 17,2
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In the present study we
2023-08-31

In the present study we sought to decipher the role of ATP-citrate lyase and of the mitochondrial NADH-dependent Mae in the oleaginous yeast Y. lipolytica. Indeed, although this yeast is one of the major models for lipid metabolism, the function of these enzymes is still not clear. As the study of t
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Finally not only can ERs pair with different mGluRs in
2023-08-31

Finally, not only can ERs pair with different mGluRs in different Pimozide receptor regions, but it is becoming increasingly clear that the same mGluRs can pair with distinct downstream signaling partners to have differential effects both within and across brain regions (Gross et al., 2016; Mannaio
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As aforementioned this study aimed
2023-08-31

As aforementioned, this study aimed to design, synthesize and investigate aromatase inhibitory and anti-breast cancer activities of N,N′-disubstituted thiourea derivatives. Based on the attractive phenotypic molecule 1, the synthetic N,N′-disubstituted thioureas have been designed including monothio
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Introduction Antimicrobial resistance is a growing health th
2023-08-31

Introduction Antimicrobial resistance is a growing health threat worldwide that has been associated with incorrect prescription and overuse of POM 1 australia [1]. Considering that physicians play a central role in antibiotic usage, a better understanding of their prescribing behaviours and their
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br Methodology br Antibiotics in lakes br Antibiotic
2023-08-31

Methodology Antibiotics in lakes Antibiotic resistance genes in lakes Perspectives of study on Fusidic Acid sodium salt and ARGs in lakes Conclusion This paper systematically reviewed the distribution of antibiotics and ARGs in global lakes. A total of 57 antibiotics reported at least
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Cellular detoxification is an important process that
2023-08-31

Cellular detoxification is an important process that helps remove excess oxidants from the cellular environment through endogenous antioxidants or other molecules capable of reduction. One of the key regulators of antioxidant production is the transcription factor, nuclear factor (erythroid-derived
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Finally microRNAs miRNA seem to play an
2023-08-31

Finally, microRNAs (miRNA) seem to play an important role in AR signaling in BC. Some authors have described a differential 490 3 receptor of miRNAs in AR-positive BCs compared to AR-negative ones. VEGF and mTOR pathways were also reported as implicated in miRNA dysregulation, suggesting a common u
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Women are usually at risk
2023-08-31

Women are usually at risk of sleep deprivation or restriction during pregnancy, especially in the third trimester of gestation, due to the pregnancy-associated anatomic, physiological and hormonal changes (Pien and Schwab, 2004). However, several major PCI-32765 developmental events, such as the ne
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