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NBI 27914 hydrochloride receptor The identification of disti
2021-12-08
The identification of distinct expression domains in the limb suggested that these domains might have specific biological functions. We explored this possibility by determining enriched biological processes for each category using GO ontology term analysis (WebGestalt) (Zhang et al., 2005). Category
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latrunculin Fatty acids are also known to activate
2021-12-08
Fatty acids are also known to activate G-protein coupled receptors (GPCRs). LCFAs activate the GPCRs for free fatty latrunculin (FFA)1 and FFA4 (Briscoe et al., 2003; Hirasawa et al., 2005), whereas SCFAs activate FFA2 and FFA3 receptors, which are expressed in bovine neutrophils (Alarcon et al., 20
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Although unexpected based on our predictions low baseline
2021-12-08
Although unexpected based on our predictions, low baseline and post-stress cortisol being associated with high anxiety has been previously documented in both clinical and healthy populations of humans (Beaton et al., 2006; Jezova et al., 2004; Shirotsuki et al., 2009; Vingerhoets et al., 1996), and
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The cortical actin filaments are arranged in a
2021-12-07
The cortical Refametinib filaments are arranged in a network abuting the plasma membrane with a thickness of ∼190nm in living cells, that displays highly dynamic behaviors 15, 16, 17. Technical challenges, however, have hampered investigation of the detailed function dynamic interactions between th
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In this paper we demonstrate a diatomaceous
2021-12-07
In this paper, we demonstrate a toremifene sale based TLC-SERS sensing technique combined with machine learning analysis to quantitatively detect seafood allergen in real spoiled tuna samples. We fabricate a diatomaceous earth TLC plate as a separable SERS-active substrate to detect histamine in ar
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In addition to narrowing a wide
2021-12-07
In addition to narrowing a wide knowledge gap in Hh developmental biology research, improved understanding of Disp structure and function is likely to also be relevant to cancer. A growing body of evidence supports that Shh facilitates tumor–stroma communication in a range of cancers to influence tu
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br Experimental br Acknowledgements This work was financiall
2021-12-07
Experimental Acknowledgements This work was financially supported by Ministry of Knowledge and Economy (10032113) and Ministry of Education, Science and Technology (20100000297). Introduction To ensure accurate chromosome segregation, cohesion between sister chromatids must be maintained u
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Our findings demonstrated that the expression
2021-12-07
Our findings demonstrated that the expression level of full-length α1 sGC protein was higher in the malignant and benign breast tumors than that of normal tissues. Similarly, an increase in the expression of α1 sGC subunit has been detected in glioma cell lines [34]. Higher expressions of sGCα1 and
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Considering that loss of LAG expression results in increased
2021-12-07
Considering that loss of LAG-3 cytochalasin d results in increased CD4+ T cell homeostatic expansion, and that the ability of a cell to proliferate is tightly coupled to its metabolic profile, we hypothesized that LAG-3 regulates naive CD4+ T cell metabolism. Our results indicate that, indeed, Lag3
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br Introduction Methylglyoxal MG is a highly
2021-12-07
Introduction Methylglyoxal (MG) is a highly reactive dicarbonyl metabolite formed in cells mainly by the spontaneous degradation of triose phosphates, glyceraldehyde-3-phosphate, and dihydroxyacetone phosphate (Rabbani and Thornalley, 2012). It exists in a wide range of organisms, including proto
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br Materials and methods br Results br Discussion l glutamat
2021-12-07
Materials and methods Results Discussion l-glutamate is the major excitatory neurotransmitter in the brain, and is functionally involved in many processes of the nervous system which have been connected with several neurological diseases [4]. These conditions are characterized by the time-d
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To assess whether this coupling mechanisms
2021-12-07
To assess whether this coupling mechanisms might operate also in a native system of untransfected cells, we select a cell line SH-SY5Y neuroblastoma that is known to express both the dopamine transporter and the M-currents (Jiang et al., 2004; Wickenden et al., 2008). These experiments were performe
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However Gingrich and Hen reported
2021-12-06
However, Gingrich and Hen reported that absence of the gene at all stages of ontogenesis of mice may interfere with the normal developmental program and/or the organism may undergo changes in other systems to compensate for gene absence (46). In addition, potentially altered maternal behavior of GPR
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The HIF complex was initially identified as
2021-12-06
The HIF complex was initially identified as an important component of the cell machinery involved in the response and limonin synthesis to hypoxia (Semenza, 2001). Further studies have shown that HIF can also modulate whole-body energy homeostasis by controlling hypothalamic neurons (Varela et al.,
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br Conclusion The following is the supplementary data
2021-12-06
Conclusion The following is the supplementary data related to this article. Conflict of interest Author contributions Heart transplantation is the most important treatment for end-stage heart failure. Ischemia/reperfusion injury is a common condition during transplantation surgery and is
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