• It was thus found that E plays an important

  2019-09-17

  

  It was thus found that E1 plays an important role in G. intestinalis biology. Inhibiting E1 expression by RNA antisense in trophozoites was lethal while E1 overexpression induced a five-fold increase in cyst formation during encystation. The changes in E1 location during this process and its localiz

• In normal cells the apoptotic

  2019-09-17

  

  In normal cells, the apoptotic stimuli lower the expression level of antiapoptotic proteins by increasing turnover rate and preventing the constant degradation of proapoptotic proteins. Thus, the dysregulation of anti-/pro-apoptotic proteins will confer the survival of cancer p53 tumor suppressor vi

• The nuclear receptor related protein Nurr NR

  2019-09-17

  

  The nuclear receptor related-1 protein, Nurr1 (NR4A2), is a transcription factor that regulates the dpat of genes critical for the development, maintenance, and survival of dopaminergic neurons (Alavian et al., 2014, Decressac et al., 2013, Dong et al., 2016, Jankovic et al., 2005, Johnson et al., 2

• (-)-epicatechin br Introduction br Literature review and hyp

  2019-09-17

  

  Introduction Literature review and (-)-epicatechin development CPA exam performance-related research has been of interest to academics for the past few decades. These studies have ranged from investigating the impact of the 150-hour requirement on pass rates (Allen & Woodland, 2006) to examin

• Since cognitive disturbances are core features of PTSD and i

  2019-09-17

  

  Since cognitive disturbances are core features of PTSD [3,4], and in some studies COMT Val158/108Met was associated with cognition [10] and hippocampal volume [12], the hypothesis was that carriers of the Met allele will show better cognitive performance compared to Val/Val carriers in PTSD. The aim

• br Funding This work was supported by the grants

  2019-09-16

  

  Funding This work was supported by the grants from MSD, Terumo Life Science Foundation, Takeda Science Foundation, and Japan Diabetes Foundation. Disclosures Acknowledgments The authors thank C. Morimoto (Juntendo University, Tokyo, Japan) and K. Takeda (Immunology Frontier Research Center

• br As mentioned above defects in

  2019-09-16

  

  As mentioned above, defects in the DNA ligase IIIα-interacting protein TDP1 have been identified as the cause of the hereditary neurodegenerative disease, spinocerebellar ataxia with axonal neuropathy 1 (El-Khamisy et al., 2005). In addition, defects in two other DNA repair proteins, aprataxin and

• br Acknowledgements br Introduction Chemokines

  2019-09-16

  

  Acknowledgements Introduction Chemokines are a superfamily of chemotactic cytokines that play important roles in regulating cell migration and activation under inflammatory conditions (Nomiyama et al., 2008; Peatman and Liu, 2007; Zlotnik and Yoshie, 2000), such as angiogenesis (Arenberg et al

• Nevertheless because of the preclinical work and the interfe

  2019-09-12

  Nevertheless, because of the preclinical work and the interference with EWS–FLI1 transcriptional activity, we believe that there may be a role for ET-743 in Ewing sarcoma.

• NHS-Biotin The main variable of the

  2019-09-11

  The main variable of the study was whether there was an association between the COMT Val158Met polymorphism and motor behavior.

• We have previously shown that sustained

  2019-09-10

  We have previously shown that sustained 8-pCPT treatment favored Ca2+-dependent arrhythmogenic activity in rat ventricular cardiomyocytes [8].

• CCK-8 Magnetic interactions between metal ions are

  2019-09-09

  Magnetic interactions between metal ions are usually described by superexchange via intermediate ligands.

• br Conclusions When the authors joined the

  2019-09-07

  Conclusions When the authors joined the field of oxysterol analysis around the turn of the century, oxysterols and cholestenoic acids were mostly considered as uninteresting intermediates of cholesterol metabolism.

• Our results in the present study demonstrate that

  2019-09-06

  Our results in the present study demonstrate that CysLT1 mediates leukotriene-induced contraction in the fundus and suggest that both CysLT1 and CysLT2 mediate leukotriene-induced contraction in the antrum in vitro.

• br Results br Discussion We first tested for

  2019-09-05

  Discussion We first tested for any adverse effect of ATR on learning and memory with a MWM test, which is used to assess hippocampal spatial learning and memory abilities in rodents (Vorhees and Williams, 2006).

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