Although DAPK has been implicated in neuronal death in ische

2019-08-15

Although DAPK has been implicated in neuronal death in ischemic stroke and neurodegenerative diseases, such as Alzheimer’s disease (Shamloo et al., 2005, Duan et al., 2013), the mechanisms about how DAPK regulates cell death are still elusive.

Several CHK inhibitors have been

2019-08-14

Several CHK-1 inhibitors have been reported in the literature. Of these, UCN-01 (7-hydroxystaurosporine) is a potent inhibitor of CHK-1 (=5.6nM), , and has modest selectivity among other kinases. UCN-01 is currently in clinical trials.

br Significance Our understanding of the ubiquitin biology h

2019-08-13

Significance Our understanding of the ubiquitin biology has been rapidly expanding.

Hello world!

2018-07-29